Elastic model for dinucleosome structure and energy.
نویسندگان
چکیده
The equilibrium structure of a dinucleosome is studied using an elastic model that takes into account the force and torque balance conditions. Using the proper boundary conditions, it is found that the conformational energy of the problem does not depend on the length of the linker DNA. In addition it is shown that the two histone octamers are almost perpendicular to each other, and the linker DNA in short lengths is almost straight. These findings could shed some light on the role of DNA elasticity in the chromatin structure.
منابع مشابه
Study of Stone-wales Defect on Elastic Properties of Single-layer Graphene Sheets by an Atomistic based Finite Element Model
In this paper, an atomistic based finite element model is developed to investigate the influence of topological defects on mechanical properties of graphene. The general in-plane stiffness matrix of the hexagonal network structure of graphene is found. Effective elastic modulus of a carbon ring is determined from the equivalence of molecular potential energy related to stretch and angular defor...
متن کاملSoil Structure Interaction Effects on Hysteretic Energy Demand for Stiffness Degrading Systems Built on Flexible Soil Sites
This paper aims to study the influence of soil-structure interaction on plastic energy demand spectra directly derived from the energy-balance equations of soil-shallow-foundation structure with respect to an ensemble of far-field strong ground motions obtained from Pacific Earthquake Engineering Research (PEER) database and recorded on alluvium soil. The superstructure is modeled as a single-d...
متن کاملWave Propagation at the Boundary Surface of Elastic Layer Overlaying a Thermoelastic Without Energy Dissipation Half-space
The present investigation is to study the surface wave propagation at imperfect boundary between an isotropic thermoelastic without energy dissipation half-space and an isotropic elastic layer of finite thickness. The penetration depth of longitudinal, transverse, and thermal waves has been obtained. The secular equation for surface waves in compact form is derived after developing the mathemat...
متن کاملProtectin and resolvin gut inflammation
In eukaryotic cells, genomic DNA must be compacted to fit inside the nucleus. A key player in DNA packaging is the nucleosome, which comprises a segment of DNA wrapped around an octamer of histone proteins. During replication and transcription, nucleosomes must reposition themselves on the DNA. In this process, nucleosomes can collide to form a dinucleosome. Kato et al. report a high-resolution...
متن کاملEffect of Rotation and Stiffness on Surface Wave Propagation in a Elastic Layer Lying Over a Generalized Thermodiffusive Elastic Half-Space with Imperfect Boundary
The present investigation is to study the surface waves propagation with imperfect boundary between an isotropic elastic layer of finite thickness and a homogenous isotropic thermodiffusive elastic half- space with rotation in the context of Green-Lindsay (G-L model) theory. The secular equation for surface waves in compact form is derived after developing the mathematical model. The phase velo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Physical review. E
دوره 93 شماره
صفحات -
تاریخ انتشار 2016